| City League Class 6A/5A/4A/3A |
| 7:00pm | Brashear at Westinghouse | 0-64 |
| Non Conference |
| 7:00pm | Aliquippa at Avonworth | 46-20 |
| 7:00pm | Ambridge at Hopewell | 34-35 OT |
| 7:00pm | Baldwin at West Mifflin | 0-49 |
| 7:00pm | Beaver Area at Imani Christian | 28-42 |
| 7:00pm | Bentworth at Charleroi | 35-28 |
| 7:00pm | Bethel Park at Armstrong | 46-7 |
| 7:00pm | Burgettstown at Jefferson-Morgan | 14-49 |
| 7:00pm | Burrell at Mount Pleasant | 13-23 |
| 7:00pm | Butler at Meadville | 35-11 |
| 7:00pm | Canon-McMillan at South Fayette | 10-13 |
| 7:00pm | Carlynton at South Allegheny | 13-37 |
| 7:00pm | Central Catholic at Woodland Hills | 54-14 |
| 7:00pm | Central Valley at Belle Vernon | 17-23 |
| 7:00pm | Chartiers Valley at Indiana | 62-0 |
| 7:00pm | Clairton at Shady Side Academy | 50-0 |
| 7:00pm | Connellsville at Albert Gallatin | 26-29 |
| 7:00pm | Deer Lakes at Derry Area | 34-12 |
| 7:00pm | Elizabeth Forward at East Allegheny | 41-14 |
| 7:00pm | Ellwood City at Neshannock | 28-21 |
| 7:00pm | Fort Cherry at West Greene | 41-0 |
| 7:00pm | Franklin Regional at Upper St. Clair | 7-45 |
| 7:00pm | Frazier at Carmichaels | 20-50 |
| 7:00pm | Gateway at Plum | 22-15 |
| 7:00pm | Greensburg Central Catholic at Apollo-Ridge | PPD |
| 7:00pm | Hempfield at Kiski Area | 31-29 |
| 7:00pm | Highlands at New Castle | PPD |
| 7:00pm | Jeannette at Ligonier Valley | 34-27 |
| 7:00pm | Keystone Oaks at South Park | 6-42 |
| 7:00pm | Knoch at Fox Chapel | PPD |
| 7:00pm | Latrobe at Norwin | 42-28 |
| 7:00pm | Leechburg at Serra Catholic | 48-27 |
| 7:00pm | Mapletown at Chartiers-Houston | 12-48 |
| 7:00pm | McGuffey at West Allegheny | PPD |
| 7:00pm | McKeesport at Thomas Jefferson | 31-34 OT |
| 7:00pm | Mohawk at Shenango | PPD |
| 7:00pm | Monessen at Beth-Center | 56-30 |
| 7:00pm | Montour at Trinity | 14-7 |
| 7:30pm | Moon at Penn-Trafford | 7-14 |
| 7:00pm | North Allegheny at Penn Hills | 18-14 |
| 7:00pm | North Hills at Mars | 21-17 |
| 7:00pm | Peters Township at Mt. Lebanon | 28-0 |
| 7:00pm | Pine-Richland at Seneca Valley | PPD |
| 7:00pm | Seton LaSalle at Our Lady of Sacred Heart | PPD |
| 7:00pm | Southmoreland at Laurel Highlands | 49-13 |
| 7:00pm | Springdale at Avella | 0-44 |
| 7:00pm | Steel Valley at Bishop Canevin | 6-42 |
| 7:00pm | Sto-Rox at Brentwood | 14-21 |
| 7:00pm | Summit Academy at Freedom | PPD |
| 7:00pm | Union at Washington | 6-35 |
| 3:30pm | Uniontown at Carrick | 34-0 |
| 7:00pm | Valley at Greensburg Salem | 14-50 |
| 7:00pm | Waynesburg Central at California | 28-18 |
| 7:00pm | Ringgold at Yough | 21-19 |
