| Non Conference |
| 7:00pm | Allderdice at Butler | 0-36 |
| 7:00pm | Ambridge at Uniontown | 13-21 |
| 7:00pm | Armstrong at Hampton | 27-20 |
| 7:00pm | Avonworth at Central Valley | 28-14 |
| 7:00pm | Beaver Area at Blackhawk | 40-55 |
| 7:00pm | Belle Vernon at Our Lady of Sacred Heart | 35-0 |
| 7:00pm | Bentworth at Jefferson-Morgan | 41-21 |
| 7:00pm | Brashear at Martins Ferry, Ohio | 15-53 |
| 7:00pm | Brentwood at Ligonier Valley | 18-34 |
| 7:00pm | Brownsville at West Greene | 6-50 |
| 7:00pm | Burgettstown at Avella | 32-0 |
| 7:00pm | Burrell at South Park | 27-26 |
| 7:00pm | California at Fort Cherry | 14-43 |
| 7:00pm | Carlynton at Charleroi | 12-47 |
| 7:00pm | Carrick at Baldwin | 12-29 |
| 7:00pm | Central Catholic at Woodland Hills | 45-0 |
| 7:00pm | Chartiers-Houston at Waynesburg Central | 14-27 |
| 7:00pm | Connellsville at Albert Gallatin | 28-33 |
| 7:00pm | Cornell at Leechburg | 21-9 |
| 7:00pm | Deer Lakes at West Mifflin | 0-35 |
| 7:00pm | Elizabeth Forward at North Catholic | 34-28 2OT |
| 7:00pm | Fox Chapel at Shaler | 10-24 |
| 7:00pm | Frazier at Keystone Oaks | 33-25 |
| 7:00pm | Freeport at Ellwood City | 45-7 |
| 7:00pm | Gateway at Penn Hills | 34-33 |
| 7:00pm | Greensburg Central Catholic at Apollo-Ridge | 6-42 |
| 7:00pm | Greensburg Salem at Indiana | 27-42 |
| 7:00pm | Hopewell at Chartiers Valley | 35-20 |
| 7:00pm | Jeannette at Southmoreland | 33-0 |
| 7:00pm | Kiski Area at Highlands | 22-45 |
| 7:00pm | Laurel at Mohawk | 28-6 |
| 7:00pm | Laurel Highlands at Derry Area | 25-29 |
| 7:00pm | Mapletown at East Allegheny | 6-42 |
| 7:00pm | Mars at Aliquippa | 27-42 |
| 7:00pm | McGuffey at Knoch | 20-21 |
| 7:00pm | McKeesport at Montour | 17-28 |
| 7:00pm | Monessen at Carmichaels | 38-0 |
| 7:00pm | Mount Pleasant at Yough | 47-14 |
| 7:00pm | Neshannock at Bishop Canevin | 7-55 |
| 7:00pm | New Brighton at Union | 42-21 |
| 7:00pm | New Castle at Propel Braddock Hills | 28-48 |
| 7:30pm | Norwin at Latrobe | 38-28 |
| 7:00pm | Peters Township at South Fayette | 0-14 |
| 7:00pm | Plum at Franklin Regional | 42-20 |
| 7:00pm | Quaker Valley at Freedom | 8-35 |
| 7:00pm | Ringgold at Valley | 53-7 |
| 7:00pm | Riverside at South Side | 26-0 |
| 7:00pm | Serra Catholic at Northgate | 6-13 |
| 7:00pm | Seton LaSalle at Western Beaver | 55-7 |
| 7:00pm | South Allegheny at Washington | 20-55 |
| 7:00pm | Steel Valley at Clairton | 1-0 F |
| 7:00pm | Steelton-Highspire at Westinghouse | 6-33 |
| 7:00pm | Sto-Rox at Rochester | 36-28 |
| 7:00pm | Thomas Jefferson at Mt. Lebanon | PPD |
| 7:00pm | Trinity at Canon-McMillan | 29-24 |
| 7:00pm | University Prep at Girard, Ohio | 6-39 |
| 7:30pm | Upper St. Clair at North Allegheny | 21-14 |
| 7:00pm | West Allegheny at Pine-Richland | 20-59 |
