| Non Conference |
| 7:00pm | Aliquippa at Seton LaSalle | 0-28 |
| 7:00pm | Apollo-Ridge at Freeport | 30-35 |
| 7:00pm | Avella at Charleroi | 8-24 |
| 7:00pm | Baldwin at Brashear | 10-24 |
| 7:00pm | Beaver Falls at Cornell | 32-6 |
| 7:00pm | Belle Vernon at West Mifflin | 19-12 |
| 7:00pm | Bethel Park at North Hills | 6-29 |
| 7:00pm | Bishop Canevin at Shady Side Academy | 42-3 |
| 7:00pm | Brownsville at Carlynton | 14-63 |
| 7:00pm | Butler at Meadville | 23-0 |
| 7:00pm | Canon-McMillan at Upper St. Clair | 10-21 |
| 7:00pm | Central Valley at Shaler | 34-17 |
| 7:00pm | Chartiers Valley at Mars | 38-24 |
| 7:00pm | Connellsville at Laurel Highlands | 28-14 |
| 7:00pm | East Allegheny at Derry Area | 7-37 |
| 7:00pm | Ellwood City at Avonworth | 6-55 |
| 7:00pm | Fort Cherry at Laurel | 21-17 |
| 7:00pm | Franklin Regional at Norwin | 7-54 |
| 7:00pm | Frazier at Monessen | 14-20 |
| 7:00pm | Freedom at Deer Lakes | 55-48 |
| 7:00pm | Gateway at West Allegheny | 10-49 |
| 7:00pm | Greensburg Central Catholic at Carmichaels | 41-8 |
| 7:00pm | Greensburg Salem at Burrell | 39-42 |
| 7:00pm | Hampton at Ringgold | 24-14 |
| 7:00pm | Highlands at Beaver Area | 31-35 |
| 7:00pm | Hopewell at Propel Braddock Hills | 21-28 |
| 7:00pm | Indiana at Latrobe | 7-45 |
| 7:00pm | Jeannette at New Brighton | 28-14 |
| 7:00pm | Jefferson-Morgan at Chartiers-Houston | 7-63 |
| 7:00pm | Keystone Oaks at Bentworth | 20-28 |
| 7:00pm | Kiski Area at Armstrong | 28-35 |
| 7:00pm | Knoch at Ambridge | 34-20 |
| 7:00pm | Leechburg at Beth-Center | 13-46 |
| 7:00pm | Ligonier Valley at Yough | 45-0 |
| 7:00pm | Mapletown at Serra Catholic | 14-54 |
| 7:00pm | McKeesport at Thomas Jefferson | 33-40 |
| 7:00pm | Mohawk at Shenango | 7-35 |
| 7:00pm | Montour at South Fayette | 28-35 |
| 7:00pm | Mount Pleasant at South Allegheny | 3-41 |
| 7:00pm | Mt. Lebanon at Peters Township | 0-16 |
| 7:00pm | North Catholic at New Castle | 7-43 |
| 7:00pm | Northgate at Brentwood | 7-21 |
| 7:00pm | Our Lady of Sacred Heart at Blackhawk | 12-43 |
| 7:00pm | Penn Hills at Seneca Valley | 6-42 |
| 7:00pm | Penn-Trafford at Moon | 22-7 |
| 7:00pm | Pine-Richland at Central Catholic | 24-48 |
| 7:00pm | Plum at Fox Chapel | 49-0 |
| 7:00pm | Riverview at Riverside | 6-40 |
| 7:00pm | Rochester at Burgettstown | 0-37 |
| 7:00pm | South Side at Neshannock | 29-48 |
| 7:00pm | Summit Academy at Sto-Rox | 0-74 |
| 7:00pm | Trinity at Hempfield | 20-44 |
| 7:00pm | Union at Springdale | 42-0 |
| 7:00pm | Uniontown at Southmoreland | 21-42 |
| 7:00pm | Valley at Quaker Valley | 41-0 |
| 7:00pm | Washington at California | 50-6 |
| 7:00pm | Waynesburg Central at Albert Gallatin | 35-0 |
| 7:00pm | West Greene at McGuffey | 0-48 |
| 7:00pm | Western Beaver at Steel Valley | 7-14 |
| 7:30pm | Woodland Hills at North Allegheny | 33-25 |
