| Class 6A |
| Quad County Conference |
| 7:00pm | Hempfield at Norwin | |
| 7:00pm | Mt. Lebanon at Seneca Valley | |
| 7:00pm | North Allegheny at Central Catholic | |
| Class 5A |
| Allegheny Six Conference |
| 7:00pm | Thomas Jefferson at West Allegheny | |
| 7:00pm | Trinity at Peters Township | |
| 7:00pm | Upper St. Clair at Bethel Park | |
| Big East Conference |
| 7:00pm | Connellsville at Gateway | |
| 7:00pm | Franklin Regional at Latrobe | |
| 7:00pm | Penn-Trafford at Fox Chapel | |
| Northeast Conference |
| 7:00pm | Moon at Plum | |
| 7:00pm | North Hills at Armstrong | |
| 7:00pm | Penn Hills at Pine-Richland | |
| Class 4A |
| Big Six Conference |
| 7:00pm | Laurel Highlands at Chartiers Valley | |
| 7:00pm | Mount Pleasant at Belle Vernon | |
| 7:00pm | South Fayette at Albert Gallatin | |
| Greater Allegheny Conference |
| 7:00pm | Blackhawk at Mars | |
| 7:00pm | Indiana at Shaler | |
| 7:00pm | Kiski Area at Hampton | |
| Parkway Conference |
| 7:00pm | New Castle at Montour | |
| Class 3A |
| Allegheny Seven Conference |
| 7:00pm | Burrell at Knoch | |
| 7:00pm | Deer Lakes at North Catholic | |
| 7:00pm | Freeport at Valley | |
| Interstate Conference |
| 7:00pm | Derry Area at Elizabeth Forward | |
| 7:00pm | Waynesburg Central at Greensburg Salem | |
| Three Rivers Conference |
| 7:00pm | Avonworth at Shady Side Academy | |
| 7:00pm | Propel Braddock Hills at West Mifflin | |
| 7:00pm | South Park at Yough | |
| Western Hills Conference |
| 7:00pm | Beaver Area at Ambridge | |
| 7:00pm | Ellwood City at Hopewell | |
| 7:00pm | Our Lady of Sacred Heart at Aliquippa | |
| Class 2A |
| Allegheny Conference |
| 7:00pm | Brownsville at Steel Valley | |
| 7:00pm | South Allegheny at Charleroi | |
| Century Conference |
| 7:00pm | Keystone Oaks at Carlynton | |
| 7:00pm | McGuffey at Seton LaSalle | |
| Midwestern Conference |
| 7:00pm | Freedom at Riverside | |
| 7:00pm | Mohawk at Western Beaver | |
| 7:00pm | Neshannock at Beaver Falls | |
| Class 1A |
| Big 7 Conference |
| 7:00pm | Cornell at Shenango | |
| 7:00pm | Laurel at Northgate | |
| 7:00pm | Rochester at Union | |
| Black Hills Conference |
| 7:00pm | Bentworth at Fort Cherry | |
| 7:00pm | Brentwood at Sto-Rox | |
| 7:00pm | Burgettstown at Washington | |
| 7:00pm | Quaker Valley at Bishop Canevin | |
| Eastern Conference |
| 7:00pm | Jeannette at Greensburg Central Catholic | |
| 7:00pm | Riverview at Serra Catholic | |
| 7:00pm | Springdale at Clairton | |
| Tri-County South Conference |
| 7:00pm | Avella at Jefferson-Morgan | |
| 7:00pm | Beth-Center at Carmichaels | |
| 7:00pm | Mapletown at Frazier | |
| 7:00pm | West Greene at California | |
| City League Class 6A/5A/4A/3A/2A City League |
| 3:30pm | Perry Traditional Academy at Allderdice | |
| 7:00pm | University Prep at Carrick | |
| Non Conference |
| 7:00pm | Baldwin at Butler | |
| 7:00pm | Chartiers-Houston at Apollo-Ridge | |
| 7:00pm | McKeesport at Central Valley | |
| 7:00pm | Monessen at Leechburg | |
| 7:00pm | Southmoreland at Highlands | |
| 7:00pm | Woodland Hills at Canon-McMillan | |
