| Class 6A |
| Section 1 (6A) |
| 7:30pm | Woodland Hills at Seneca Valley | 21-48 |
| Section 2 (6A) |
| 7:00pm | Hempfield at Upper St. Clair | 55-75 |
| Class 5A |
| Section 1 (5A) |
| 5:30pm | Fox Chapel at Shaler | 45-62 |
| 7:30pm | Franklin Regional at Armstrong | 63-36 |
| 7:30pm | Gateway at Plum | 13-46 |
| Section 2 (5A) |
| 7:30pm | Greensburg Salem at Latrobe | 46-54 |
| 7:30pm | Indiana at West Mifflin | 48-27 |
| 7:30pm | Kiski Area at Penn-Trafford | 22-55 |
| Section 3 (5A) |
| 7:30pm | Chartiers Valley at South Fayette | 41-72 |
| 7:30pm | Moon at West Allegheny | 53-48 |
| 7:30pm | New Castle at Mars | 31-62 |
| Section 4 (5A) |
| 7:30pm | Peters Township at Uniontown | 62-21 |
| 7:30pm | Trinity at Albert Gallatin | 48-43 |
| Class 4A |
| Section 1 (4A) |
| 7:30pm | Freeport at Highlands | 53-63 |
| 7:30pm | North Catholic at Knoch | 65-22 |
| 7:00pm | Oakland Catholic at Derry Area | 46-19 |
| 7:30pm | Valley at Burrell | 36-54 |
| Section 2 (4A) |
| 7:30pm | Central Valley at Ambridge | 52-7 |
| 7:30pm | Hampton at Blackhawk | 22-62 |
| 7:30pm | Lincoln Park at Beaver Area | 31-49 |
| Section 3 (4A) |
| 7:30pm | Elizabeth Forward at Yough | 56-21 |
| 7:30pm | Laurel Highlands at Ringgold | 72-13 |
| 7:00pm | Mount Pleasant at Belle Vernon | 18-41 |
| 7:00pm | Southmoreland at South Park | 16-66 |
| Class 3A |
| Section 1 (3A) |
| 7:30pm | Mohawk at Quaker Valley | 6-51 |
| 7:30pm | New Brighton at Our Lady of Sacred Heart | 12-71 |
| 6:30pm | Sto-Rox at Riverside | 27-55 |
| Section 2 (3A) |
| 7:15pm | East Allegheny at Ligonier Valley | 17-51 |
| 7:30pm | Greensburg Central Catholic at Shady Side Academy | 33-62 |
| 7:30pm | South Allegheny at Avonworth | 4-54 |
| 7:30pm | Steel Valley at Deer Lakes | 15-52 |
| Section 3 (3A) |
| 7:00pm | Charleroi at Brownsville | 24-56 |
| 7:30pm | Keystone Oaks at Waynesburg Central | 48-33 |
| 7:30pm | McGuffey at Washington | 57-50 |
| Class 2A |
| Section 1 (2A) |
| 7:30pm | Aliquippa at Freedom | 67-28 |
| 7:30pm | Laurel at Shenango | 54-30 |
| 7:30pm | Neshannock at Rochester | 69-39 |
| Section 2 (2A) |
| 7:30pm | Brentwood at Burgettstown | 45-39 |
| 7:00pm | Carlynton at South Side Beaver | 28-74 |
| 6:00pm | Fort Cherry at Northgate | 68-3 |
| Section 3 (2A) |
| 7:00pm | Bentworth at Beth-Center | 35-49 |
| 7:00pm | California at Jefferson-Morgan | 55-37 |
| 7:30pm | Carmichaels at Chartiers-Houston | 17-58 |
| Section 4 (2A) |
| 7:00pm | Apollo-Ridge at Frazier | 59-30 |
| 7:00pm | Jeannette at Winchester Thurston | 20-62 |
| Class 1A |
| Section 1 (1A) |
| 7:00pm | Eden Christian at Aquinas Academy | 28-63 |
| 5:30pm | Leechburg at Union | 15-64 |
| 6:30pm | St. Joseph at Sewickley Academy | 59-31 |
| 7:00pm | Western Beaver at Springdale | 31-42 |
| Section 2 (1A) |
| 7:30pm | Bishop Canevin at Avella | 54-37 |
| 6:00pm | Clairton at Mapletown | 72-34 |
| 7:00pm | Geibel Catholic at Monessen | 50-25 |
| Non Conference |
| 5:00pm | Grace Christian School at Propel Montour | PPD |
| TBD | Nazareth Prep at Hillcrest Christian Academy | PPD |
| 4:00pm | Neighborhood Academy at Trinity Christian | 8-45 |
| 4:00pm | Propel Braddock Hills at Redeemer Lutheran | PPD |
